WHAT ARE THE THINGS IN BLOOD?

  WHAT ARE THE THINGS IN BLOOD?

We all have seen blood before either from ourselves or others, right? We either injured ourselves from cutting anything like when we were using scissors, knives, or any sharp tools. If you haven’t seen blood before, I am afraid for you because how could you not have seen blood before? Either way, we all understand and acknowledge the presence of blood in our body. Surprisingly enough, blood is all over our body, from head to toe.

   Did you know that we have almost 1.5 gallons of blood in our body or for the medical term, we can extract almost 10 units of blood in our body. The amount of blood in everyone’s body differs from each other. The average amount of blood in our body is an estimate because it can depend on how much we weigh, our sex and even where we live. Like I said, it differs because of these factors.

   For example, babies who are born full term only have about 75 millilitres of blood per kilogram of their body weight and if the baby weights around 4 kilograms, they will have about 270 mL of blood in their body whilst in children the average 40 kilograms child will have about 2,650 mL of blood in their body. 



   As us, who are adults that weight around 80 kilograms should have about 5,700 mL but for pregnant women, they are different. For them, they have to support the growing babies, the pregnant mother usually has somewhere around 30 to 50 percent more blood volume than women who are not pregnant. This is why we call all of the moms out there, that they are supermoms!



   Unfortunately, there are cases in where you can lose blood. You might be thinking, how much of blood can we lose? It depends but put in mind that if our brain doesn’t get enough oxygen to support you, that shows that you lose too much blood. There are people who goes through major injury and trauma such as car accident. This may cause loss of blood very quickly. Losing a big amount of blood is known as haemorrhagic shock but we are not here to talk about haemorrhagic shock or how we can lose blood, we are here to tell you about what the components in blood are.

   Blood is a specialized body fluid and as simple blood may seem, which everyone might just think, “Oh, it’s blood. It has a red colour. What is so special about it anyways?”



   Surprisingly there are four main components in blood which we are going to learn today. There is plasma, red blood cells, white blood cells and platelets. Please, remember these main components because you will hear a lot of these through out this article.



    Red blood cells, which are the most numerous living cells in blood, carry waste products to the kidneys and liver, which filter and clean the blood. Blood also serves many other functions, including transporting oxygen and nutrients to the lungs and tissues, which are also referred to as connective tissue, forming blood clots to prevent excessive blood loss, carrying cells and antibodies that can fight infection, and regulating body temperature. Whole blood, a mixture of roughly 45 percent blood cells and 55 percent plasma, is the blood that flows through the veins, arteries, and capillaries. Blood makes up about 7 to 8% of our whole-body weight, as I previously stated.

   In my university, they occasionally held events to donate blood to the hospital for others to use but haematology, the study of blood encompasses much more than this. Blood contains white blood cells which are monocytes, lymphocytes, neutrophils, eosinophils, basophils, macrophages. We also have the erythrocytes, and thrombocytes.



   Each of them has different functions in our body. Something that looks so simple has so many functions in them that helps our body.

   Let me dissect the cells one by one specifically for you so you would understand it much easier.

   Monocytes are fundamentally and mainly what we have. They are responsible for locating and eliminating germs including bacteria, fungus, viruses, and protozoa as well as any contaminated cells from our body. Monocytes ask other white blood cells for assistance in treating wounds and fending off infections. What are monocytes used for? Monocytes are the cellular fire department. They begin their life cycle in the bone marrow, where they develop and learn how to defend our body. As soon as they reach maturity, they will enter our circulation and tissues to protect our body from external attackers, as I just mentioned.

   Why are monocytes said to as our firefighters? This is due to the fact that, if we imagine germs as fire, they will generate an alarm to sound in our bodies, summoning monocytes to battle the fire. These cellular firemen can differentiate into dendritic cells and macrophages, two separate cell types.

   What carry out macrophages? Macrophages are on the front lines of the fire, combating the germs that enters our body. Invading bacteria are surrounded by macrophage cells, which then eat and digest the invader with the help of harmful enzymes. Additionally, these cells aid in the removal of dead cells from our tissues and blood. 



   We then move on to lymphocytes. Another variety of white blood cell is the lymphocyte. They are crucial to the functioning of our immune system, which aids in the body's defence against illness and infection. An extensive network of immune cells, lymph nodes, lymph tissue, and lymphatic organs makes up our immune system. Immune cells include lymphocytes. The T cells and the B cells are the two primary subtypes of lymphocytes.


   What do the roles of those two cells entail? While B cells produce antibodies, which are proteins that target viruses, bacteria, and other foreign invaders, T cells guide our body's immune system response and actively assault and kill the infected cells and tumour cells.

B CELL

T CELL


   As I just mentioned, lymphocytes support the immune system's defences against invading viruses, germs, and cancer. Our immune system benefits from lymphocytes because they keep track of every antigen it encounters. Some lymphocytes become memory cells once they have an encounter. Memory cells will recognise an antigen and react swiftly if they come into contact with it again. You don't contract an infection like measles or chickenpox more than once because of this. Additionally, it explains why vaccinations can help avoid some diseases. 

   Neutrophils are the next to come. This cell serves as the initial line of defence for our immune system. White blood cells come in three different subtypes: granulocytes, lymphocytes, and monocytes.

   Consider our immune system as the arm of our body's general responsible for guarding against the entry of bacteria and viruses. Our immune system sends its little army of mature neutrophils, eosinophils, and basophils to move through our circulation system and tissues in order to prepare for intruders that will cause illness, infection, and disease once our white blood cells complete basic training in our bone marrow. Our neutrophils arrive on the scene initially in the case of an immune system attack. By laying traps and consuming them, neutrophils will capture and kill the invasive bacteria or germs. Our body will respond to the conflict by becoming red and swollen, and our neutrophils will begin the process of tissue repair, which will heal the injury or damage. 



   Last but not least for white blood cells is basophils. Basophils: What are they? Basophils are one of the various types of white blood cells that are present in our body, as I just explained. These blood cells are the least common in all mammals and make up less than 1% of all of our circulating white blood cells. Our bone marrow produces basophils, which are cells that are a component of our immune system. The connective tissues of our body include basophils. They are able to aid in the detection and eradication of some early cancer cells. When an allergic reaction or asthma attack occurs, basophils also release the histamine stored in their granules. 



   We have covered all the white blood cells, now it’s time for us to talk about the red blood cells or the scientific name of it is erythrocytes.

   Erythrocytes have a biconcave form, which is quite reminiscent of a donut. This indicates that their outskirts are thicker than their centre.

   What makes it appear that way? Erythrocytes' primary function is to transport and exchange gases like oxygen and carbon dioxide between the tissues and the lungs.

   What causes that to occur? Oxyhaemoglobin is created in the lung capillaries when haemoglobin binds to the oxygen that we breathe. Erythrocytes and consequently arterial blood are coloured vivid red by this material. The arteries are the next stop for erythrocyte-rich oxygen before it reaches the tissue capillaries. Haemoglobin is released in tissue capillaries, where it diffuses into the tissues. At the same time, the tissues' carbon dioxide binds to haemoglobin to create deoxyhaemoglobin. Red blood cells and venous blood are coloured purple blue by this chemical. Erythrocytes that are high in carbon dioxide then migrate through veins to the heart and lungs. Haemoglobin is released from the capillaries of the lungs in exchange for a fresh dosage of oxygen.



   Last but not least, the thrombocytes. Specialized blood cells called thrombocytes regulate blood clotting. They resemble tiny, monochromatic plates. Thrombocytes produce a clot when a blood artery tears, sealing the tear to stop bleeding. As is well knowledge, thrombocytes are utilised to treat wounds and injuries.



   The process by which thrombocytes create clots consists of several steps, the first of which is adhesion, in which the bleeding site is first contacted by thrombocytes from the ruptured vessel in an effort to stop the blood flow. They then prompt us chemically to seek additional assistance. They will then undergo aggregation. More thrombocytes respond to the call in this stage, joining forces to form a clot. Don't forget about coagulation, either. In a process known as a coagulation cascade, as the thrombocytes accumulate at the site of the cut, they close up the blood vessel, fusing the platelets and fibrin together to form the clot. The scab that forms on a cut is made of fibrin.


   Hope you guys have learned a little something from the article I wrote <3

PREPARED BY  

AZHANA IZZAH BINTI AZHAR

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